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Thursday, March 8, 2018
Cannabidiol (CBD) Found To Dramatically Decrease Frequency Of Epilepsy Seizures
Even as the pharmaceutical industry has continued to develop a steady stream of new drugs for treating epilepsy, not much has changed in terms of the overall number of drug-resistant cases of the neurological disease – suggesting that the drugs just aren’t working. This is why many people are now turning to all-natural cannabidiol instead.
A recent scientific review of cannabidiol, a major constituent of the cannabis plant that’s commonly referred to as CBD, found that this powerful cannabinoid actually works better than pharmaceuticals at keeping epilepsy under control – though how it does this is still unknown.
Researchers from the United Kingdom looked at three different papers for their review discussing the clinical uses of CBD for treating multiple variations of epilepsy. The first describes a small case series in which CBD was used to treat a rare pediatric epilepsy syndrome known as febrile infection-related epilepsy syndrome, or FIRES.
CBD found in three separate studies to dramatically decrease seizure frequency
In the first study, seven children from five United States-based hospitals were given CBD as part of an investigational new drug protocol. Two of the children started taking CBD in the acute phase of the condition, which is characterized by a febrile illness followed by very frequent multi-focal seizures with refractory status epilepticus. The remaining five started taking CBD in the chronic phase, which is characterized by pharmacoresistant epilepsy marked by significant cognitive and behavioral effects.
Prior to taking CBD, all of the children had been given an average of seven anti-epileptic drugs each, as well as steroids and intravenous immunoglobulin. All but one of the child patients was assigned to adhere to either a ketogenic or modified Atkins diet, and five were given trials of multiple anesthetic agents.
After this, each of the seven was given somewhere between 15 – 25 milligrams per kilogram of CBD daily, the effects in one of the acute patients being a complete cessation of epilepticus status. The remaining five in the chronic phase saw mean decreases in seizure frequency of 91 percent after four weeks, and 65 percent after 48 weeks when compared with pre-treatment seizure frequency. (MORE)